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Mounjaro is approved for use in the UK as a weight-loss treatment when combined with a healthy diet and regular exercise

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it contributes to sustained satiety, which is further enhanced by GLP-1 medications, helping to prevent overeating and support consistent weight loss

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GLP-1 Receptor Activation The GLP-1 component suppresses appetite by signaling the hypothalamus, slows gastric emptying so food stays in the stomach longer, and improves insulin sensitivity

Importantly, these benefits occurred despite varying degrees of weight loss across the different trials and patient populations