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Overall, GLP-1 receptor agonist use was associated with a 16% lower risk of developing epilepsy

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The loss of leptins physiological actions that occurs in peripheral tissues is referred to as peripheral leptin resistance
Back Secher, A, Jelsing, J, Baquero, et al (2014) 'The arcuate nucleus mediates GLP- 1RA liraglutide- dependent weight loss', Journal Clinical Investigation , 124, 447388