retatrutide weight loss phase 2 results just delivered the first top-line 3 for a triple agonist in obesity — and the findings from TRIUMPH-4 are striking👇 RETATRUTIDE: The “Next Big Fat

These medications work by activating GLP-1 receptors, helping people feel fuller longer, eat less, and lose weight

Safety and efficacy of GLP-1 receptor agonists in T2D mellitus with advanced and end-stage kidney disease: A systematic review and meta-analysis

A meta-analysis of 49 studies in the British Journal of Sports Medicine (2018) identified this as the point of diminishing returns for muscle protein synthesis during resistance training (Morton et al., 2018, BJSM)

More importantly, GLP-1 receptor agonists modulate reward circuitry

Tirzepatide is self-administered as a subcutaneous (under the skin) injection using a single-dose pen, KwikPen, or vial with syringe, and should always be used together with diet and exercise

17 But on the downside: Appetite suppression often leads to nutrient deficiencies in vitamins, minerals, and fatty acids that support memory, mood, and nerve function