pcos semaglutide Promising for symptoms Rising use of GLP-1 medications

doi: 10.1177/1533317520953041 235 CaiHYYangDQiaoJYangJTWangZJWuMNet al

2,3 Obesity is a complex, multifactorial condition influenced by various interrelated factors, including lifestyle, medications, genetics, medical conditions, gut hormones and psychological aspects

Yet, this risk must be balanced against a largely neutral safety profile in broad observational studies and a potential for long-term benefit

EslerWPRudolphJClausTHTangWBarucciNBrownSEet al

Impaired leptin receptor signaling is a primary mechanism driving weight gain (24, 26), and the role of CCK-A receptor signaling in satiety is well established (31)

This study further evaluated the effect of GLP-1RAs@NPs-WYRGRL on macrophage polarization