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oleifera remains challenging due to variability in dosage regimens, preparation methods, and treatment durations across the seven studies reviewed

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The brand name Mounjaro is FDA-approved for T2DM treatment and, as of its most recent regulatory updates, is also approved in the United States and Europe for weight management as Zepbound.16,17 By enhancing insulin secretion and reducing appetite, tirzepatide supports both blood glucose control and weight loss

Similarly, the GIPR rs1800437 variant modulates glucose-dependent insulinotropic peptide sensitivity, a pathway that enhances semaglutide's metabolic effects in some individuals

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