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doi: 10.1002/psc.3323

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Ca 2+ /calmodulin kinase II (CaMKII) is one of the downstream mediators of Epac-dependent pathway ( Figure 3 ), indicating that CaMKII did not play a role on Epac-dependent GLP-1R signaling

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This is why many people experience nausea, constipation, or other tummy problems when they start taking it

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