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doi: 10.3389/fendo.2013.00076 6 SpitzCWinkelsHBrgerCWeberCLutgensEHanssonGKet al

In details, we evidenced separately anthropometric parameters, metabolic effects, changes in biochemical and clinical hyperandrogenism, body composition, and ectopic fat that have been reported in the available randomized controlled clinical trials (RCTs) in PCOS women with overweight/obesity

Pregnancy and breastfeeding considerations Tirzepatide is not recommended during pregnancy or breastfeeding, and the medication should be discontinued before planned conception

Microdosing follows a research-supported model that uses lower initial concentrations of GLP-1 compounds to minimize gastrointestinal side effects while maintaining metabolic benefits

Amin Acids

doi:10.3390/cimb46120872 3
