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Note: While semaglutide is an FDA-approved medication with well-characterized safety data, its use should be under appropriate medical supervision

Naltrexone is an FDA-approved medication used to treat both opioid use disorder (OUD) and alcohol use disorder (AUD)

(The remaining ~10% likely represent other scenarios, e.g

This variation is partly driven by genetics, including variants in the GLP1R, GIPR, and MC4R genes that influence how readily your body responds to appetite-suppressing signals

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