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A key question for disorders like SLE or PsA or RA is whether GLP-1 medicines might exert useful weight loss-independent benefits through reduction of inflammation, Drucker told Healio

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Wilson JM et al (2020) The dual glucose-dependent insulinotropic peptide and glucagon-like peptide-1 receptor agonist, tirzepatide, improves lipoprotein biomarkers associated with insulin resistance and cardiovascular risk in patients with type 2 diabetes

A recent study from 2017 investigated the 12-months prognosis in the cohort of NSTEMI-NOCS diabetics, previously treated by incretin-based therapy, compared with a matched cohort of NSTEMI-NOCS diabetics never treated with such therapy and results showed that 1-year mortality and adverse cardiovascular outcomes were higher in patients with NOCS-NSTEMI and type 2 diabetes mellitus as opposed to patients with NOCS-NSTEMI alone

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