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Clinical trials lasting 68 weeks and longer show that people who continue treatment are more likely to achieve and sustain meaningful weight loss compared to those who stop therapy

If you compare someones body composition before and after weight loss, its generally better after. Also making recent headlines is Ozempic face, or the tendency to have a saggy or sunken-in facial appearance after being on GLP-1 drugs

Discovery of GLP-1based drugs for the treatment of obesity

Low SCFA synthesis may exacerbate metabolic problems in dysbiotic conditions, even if glycemic control is improved when the microbial balance is altered by food, medication, or other interventions [3]

Amano M et al
