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Description
Injectable and oral forms show similar rates of serious adverse events (less than 2%), but injection users report better tolerability and compliance in real-world registries
Type 2 diabetes is a complex disease and the significant glucose control and weight loss achieved with once-weekly semaglutide compared with dulaglutide are encouraging, as more treatment options are needed. Safety Safety profiles were similar between patients given semaglutide and dulaglutide, and less than 10% of patients had to discontinue therapy prematurely due to adverse events across all treatment groups

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Targeted protein kinase A and PP-2B regulate insulin secretion through reversible phosphorylation

The American Diabetes Association Standards of Care advises caution when using these agents in patients with gastroparesis

This is a complex effect