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This explains why some patients on GLP-1 therapy may regain weight after stopping their metabolic engine has downshifted due to lean mass loss, not fat

Using a method known as "target trial emulation," they compared patients initiating GLP-1 drugs with those initiating sodium-glucose cotransporter-2 (SGLT2) inhibitors or dipeptidyl peptidase-4 (DPP4) inhibitors

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10.1084/jem.20180794 2 Abdel-HaqR.SchlachetzkiJ

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