top glp-1 drugs for type 2 diabetes 2025 Treating in 2025: A Complications-Centric Algorithm Glycemic Control The GLP-1 Revolution Continues
Description
Considering the prolonged half-life of most GLP-1 agonists currently prescribed, it is unfeasible to withhold these agents for weeks prior to surgery to achieve normalisation of gastric function with unknown impact on aspiration rates, appreciating the detrimental effects of poorer glycaemic control on withholding these agents and associated higher risk of peri/postoperative complications (major cardiovascular events, poor wound healing, increased wound infection etc.)
Utilization of PBPK Modeling Approaches to Assess DDIs Caused by Mechanisms of Actions Evaluating the mechanism of action (eg, delayed gastric emptying, reduced fat mass and inflammation, and changes in GFR)-mediated DDIs of GLP-1 RAs and a dual GLP-1/GIP RA is often challenging to control for and clinical studies are costly
(And Why It Matters for Weight Loss) GLP-1 stands for Glucagon-Like Peptide-1 , a naturally occurring hormone your body releases after you eat
In this context, residence time refers to the duration that ingested food or liquid remains within the stomach before passing into the duodenum
10.1186/s12245-022-00431-7 [DOI] [PMC free article] [PubMed] [Google Scholar]
ASHP Foundation
