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Rather than stopping entirely, you reduce to a lower maintenance dose that preserves the appetite-suppressing and metabolic benefits while minimizing side effects and cost

While we cannot be certain, Ozempic has impressive outcome data, reflected in its FDA-approved indication, that it can reduce the risk of stroke, heart attack, and other major adverse cardiovascular events (MACE) in adults with Type 2 diabetes and heart disease

Across randomized clinical trials of GLP-1 drugs involving thousands of participants, the most common side effects are consistently stomach-related including nausea, diarrhea, constipation, and vomiting, he says

Cardiovasc Res 2011;89:7278
