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Comparative studies in GLP-1R knockout and wild-type mice have shown that GLP-1-dependent signaling alters gut microbial composition, with increased abundance of Gammaproteobacteria and Firmicutes, and reduced levels of Actinobacteria and Bacteroidetes

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Glucagon Receptor : Increases energy expenditure and promotes fat oxidation

You can read the full article at The Effect of Tesofensine on Weight Loss, Appetite, Physical Activity and QOL in Obese Subjects
