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In trials where semaglutide was added on to basal insulin with or without metformin, severe hypoglycemia (requiring the assistance of another person) was reported in 1.5% of semaglutide-treated patients

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Affordable compounded tirzepatide options exist but require research to find reputable pharmacies

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In line with practice for similar agents, a washout period before planned pregnancy should be discussed with a healthcare professional Patients experiencing severe or persistent abdominal pain, signs of an allergic reaction, or significant changes in heart rate should seek prompt medical advice
