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By combining both actions, tirzepatide in Mounjaro gives a stronger effect on weight loss and blood sugar control than treatments that use GLP-1 alone

When you eat, nutrients in your gut stimulate these L-cells to release GLP-1

Overall, both are considered safe with proper medical supervision

We did not observe any age-associated differences in GLP-1 M responsiveness in male subjects

More serious risks are also possible, though rare

Symptoms of Cushing's disease can include: Weight gain, particularly in your abdomen and face Thinning skin Easy bruising Fatigue High blood pressure We run a blood test to check your hormones to reach a diagnosis