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The observations that GLP-1 receptor agonists exert anti-inflammatory actions in preclinical studies, taken together with case reports linking improvements in psoriasis with GLP-1 receptor agonist therapy, illustrates the emerging clinical implications of non-classical anti-inflammatory actions of incretin-based therapeutics.

Understanding their distinct mechanisms, clinical evidence bases, and how genetic and biomarker data inform personalized treatment selection helps patients and providers make evidence-based decisions

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