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J., Hutchinson, C
J Med Chem 58(18):73707380 Leech CA, Chepurny OG, Holz GG (2010) Epac2-dependent rap1 activation and the control of islet insulin secretion by glucagon-like peptide-1
[DOI] [PubMed] [Google Scholar] 21.Van Mechelen M, Lories RJ

Nutrient-induced cellular mechanisms of gut hormone secretion
Phase 3 trials showed about 12% body weight reduction at the highest dose less than the injectables but a meaningful option for people who dont want to inject

Future trials should standardize reproductive endpoints and systematically capture periconception exposure to enable confirmatory synthesis and individualized benefitrisk estimation
