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The best approach for most people heading into 2026: Focus on building a solid foundation of whole-food nutrition, regular physical activity, adequate sleep, and stress management

Trends Endocrinol Metab 31(6):410421

Know when to seek help

In February, Novo warned that sales could decline by 5% to 13% in 2026

Acarbose improves hypoglycemia following gastric bypass surgery without increasing glucagon-like peptide 1 levels

Mounjaro (tirzepatide), Wegovy (semaglutide), Saxenda (liraglutide), and oral semaglutide (Rybelsus) all have phase 3 trial data showing meaningful weight loss when used alongside lifestyle change
