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For example, the statement describing a 41% increase in healthy gut bacteria within 16 days isnt a data point directly observed as a result of people using Grns its likely information taken from a study on an included ingredient, like inulin or tapioca fiber, both of which can greatly benefit gut microbiota.20 This isnt to say that Grns cant improve your gut health, but it feels rather dishonest for the company to imply attribution of these statistics to its product

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The SURMOUNT-5 trial, published in 2025 in the New England Journal of Medicine, directly compared tirzepatide with semaglutide

Table 1 Signal detection for adverse events (AEs) of glucagon-like peptide-1 receptor agonists (GLP-1 RAs) with psychiatric AEs (pAEs) in the FDA Adverse Event Reporting System (FAERS) database from 2004 to 2023

He believes recruiting promising players from more crowded talent pools to represent countries where they were not born and have no prior connection in exchange for funding is an important part of the process