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GLP-1 Medical Weight Loss (Semaglutide & Tirzepatide): linical-grade injections commonly used to support appetite regulation and metabolic balance

When to contact your GP or prescribing clinician: Persistent vomiting preventing adequate hydration or nutrition Severe abdominal pain, particularly if accompanied by fever Signs of pancreatitis (severe upper abdominal pain radiating to the back)stop Wegovy immediately and seek urgent medical assessment Symptoms of gallbladder disease (right upper quadrant pain, jaundice)rapid weight loss increases gallstone risk Inability to tolerate any food or fluids for more than 24 hours Unexplained rapid heart rate or dizziness suggesting dehydration If you have diabetes and take insulin or sulfonylureas: symptoms of hypoglycaemia (sweating, shakiness, confusion) Your prescriber should monitor you regularly as per the SmPC and NICE guidance

This article examines the relationship between GLP-1 therapy and heart rate, explores the underlying mechanisms, reviews cardiovascular safety data, and provides guidance on when to seek medical advice

Use the free peptide reconstitution calculator to match exact syringe units to any vial size and BAC water volume

Reconstituted peptides should always be refrigerated and used within 30 days

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