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Heart Health & Cardiovascular Protection Surprisingly, GLP-1 also supports heart health

doi: 10.1111/j.1463-1326.2010.01350.x 13 TaskinenM-RRosenstockJTamminenIKubiakRPatelSDugiKAet al

BMS-345541 is a highly selective inhibitor of I kappa B kinase that binds at an allosteric site of the enzyme and blocks NF-kappa B-dependent transcription in mice
Amgen is developing a GLP-1/GIP dual agonist called MariTide (currently in phase 3 trials expected to complete in 2027), which is administered as a once-monthly injection

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