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Tirzepatide deep-dive Tirzepatide is made by Eli Lilly under two brand names: Mounjaro -- weekly injection, FDA-approved for type 2 diabetes in 2022 (doses 2.5 mg through 15 mg) Zepbound -- weekly injection, FDA-approved for chronic weight management in November 2023 [4] The headline trial is SURMOUNT-1: 2,539 adults without diabetes, BMI of 30 or higher (or 27 with a weight-related condition), randomized across three tirzepatide doses (5, 10, 15 mg) versus placebo for 72 weeks

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Un 5%, de estos pacientes haba presentado al menos 1 episodio de hipoglicemia severa en los ltimos 3 meses, aun aquellos con buen control metablico (HbA1c 9%)13

Dietary modifications represent the first-line approach for managing delayed gastric emptying effects: Eat smaller, more frequent meals rather than three large meals dailythis reduces the volume of food in the stomach at any one time Choose easily digestible foods that are lower in fat and fibre, as these empty from the stomach more readily Avoid lying down immediately after eating