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Dietary support in these trials is minimal and not culturally tailored

Future GLP-1 receptor agonists may have greater neuroprotective effects

Consider requesting a referral to a registered dietitian through your GP, particularly if you have diabetes or other nutritional considerations

Resistance training leads to large improvements in strength and moderate improvements in physical function in adults who are overweight or obese: a systematic review

Statistical analysis Events of reported pancreatitis and exposure (patient years) to either incretin-based drugs (GLP-1 receptor agonists or DPP-4 inhibitors) or non-incretin-based comparator drugs/placebo were compared using contingency table analysis, calculating the ORs, 95% CIs and p values for the comparison, using GraphPad Prism version 5.02 for Windows (GraphPad Software, San Diego, CA, USA

If retatrutide does not work for your specific physiology, if the side effects are not manageable, or if access becomes difficult, you can switch back to tirzepatide using the same washout principles in reverse