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DeFronzo R, Fleck P, Wilson C, Mekki Q

While GLP-1 agonists are not addictive in the same way that opioids are, the addiction to having a slimmer body image and the potential for widespread dependency, coupled with unknown long-term risks, suggests that we should proceed with caution
It is also worth noting that psoriasis itself doesnt seem to worsen the side effects of semaglutide

Tirzepatide, approved for T2DM and obesity, achieves data-proven superior glycemic control (HbA1c reductions of 2.02.5%) and weight loss (1520% of body weight) compared to GLP-1 agonists, such as semaglutide [14]

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Fluid retention and heart failure can occur with concomitant use of thiazolidinediones (TZDs), which are PPAR-gamma agonists, and insulin, including Fiasp
