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Others explore microdosing tirzepatide as a maintenance strategy after reaching their target weight

A dipeptidyl peptidase-4 inhibitor, des-fluoro-sitagliptin, improves endothelial function and reduces atherosclerotic lesion formation in apolipoprotein E-deficient mice

10.1038/s41598-017-17718-y Sci

Table 1 summarize these effects

Excess body weight significantly increases pressure on weight-bearing joints, especially the knees and hips
