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During this time, adults taking a weight loss drug in clinical trials lost an average of about 10 percent of their starting body weight, and they lost an additional eight percent within 15 months

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The STEP (Semaglutide Treatment Effect in People with obesity) trials demonstrated that weight loss achieved with semaglutide can lead to reductions in alanine aminotransferase (ALT) and aspartate aminotransferase (AST)liver enzymes that, when elevated, indicate hepatic inflammation or damage

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