glp-1 aging Gut Longevity+ GLP-1 Receptor Agonists and the

Metformin, the current first-line treatment in T2DM, has an unclear antidepressant effect [166] despite identified direct mechanisms and pleiotropic effects, including inhibition of angiotensin II and NF-B factor, normalization of gut microbiota, and intestinal permeabilization, and in vivo experimental data [167] supporting its potential benefits

Semaglutide is best for those searching for a permanent weight loss solution vs

Sources: GoodRx and CNN

Urgent referral (within 2 weeks) is needed for sudden hearing loss with tinnitus that developed within the last 30 days, pulsatile tinnitus (tinnitus that beats in time with your pulse), or unilateral tinnitus with asymmetrical hearing loss

Beta-cell function progressively declines, often necessitating treatment intensification over time to maintain glycemic control

For those also making supportive lifestyle changes like changing their diet and increasing their exercise, progress often feels more noticeable during this time