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If HbA1c doesn't improve after 3 months on medication, dosing or approach may need adjustment

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Because the main site of absorption for oral semaglutide is the stomach, the pharmacokinetics of oral semaglutide in people with type 2 diabetes and upper GI disease (chronic gastritis and/or gastroesophageal reflux disease) was assessed in a phase 1, open-label, parallel-group trial (52)