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To keep the medication working, do not reuse needles

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Because of their intermittent stimulation of the GLP-1R, short-acting GLP-1RAs retain their ability to delay gastric emptying leading to lower postprandial glucose excursions compared with the long-acting GLP-1RAs, which are associated with the development of tolerance (tachyphylaxis) to GLP-1s effect on gastric emptying (10)