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While these drugs offer proven cardiovascular benefits, clinical trials consistently show a modest heart rate increase of 14 beats per minute in most patients

Use of GLP-1RAs for other conditions One thing is for sure, despite this class of medications being primarily sold for diabetes and now for weight loss, they are being investigated for much more beyond their potential use for MCAS

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doi:10.1186/s12931-016-0342-7 73

The skin of the face also loses its ability to retract after an episode of rapid weight loss due to reduced levels of elastin and collagen, which are essential for structural integrity

doi: 10.1016/j.mehy.2011.09.011
