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Multiple community reports support this observation, particularly during the higher-dose phases of the escalation schedule

M., & Zhang, L

Schedule a routine appointment to discuss skin changes that are persistent but not urgent, such as ongoing skin dryness unresponsive to moisturizers, changes in skin texture or elasticity concerning to you, or new skin lesions unrelated to injection sites

Nat Biotechnol

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Anyone considering creatine while using a GLP-1 should speak with their clinician first, especially if they have kidney concerns, diabetes-related complications, or other underlying health conditions