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Notably, Trulicity carries a higher risk of low blood sugar (hypoglycemia) when used with insulin or sulfonylureas (up to 20%), while Zepbound shows lower hypoglycemia rates (~5%)

Tirzepatide is a protein-based medicine , and proteins can break down if they are exposed to extreme temperatures

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This practice has not been clinically studied or approved, and carries substantial risks of infection and accidental overdose

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