obesity drug news today glp-1 september 22 2025 medications like Ozempic, Wegovy and Mounjaro are changing diabetes and weight management, but they aren't recommended during pregnancy or while nursing. The current recommendation is to stop before conception and discuss 6 facts about obesity and

Exenatide reduces TNF-alpha expression and improves hippocampal neuron numbers and memory in streptozotocin treated rats

The clinical significance of these interactions will be detailed in the prescribing information when orforglipron is approved, and is an important consideration for the many patients with obesity or type 2 diabetes who take multiple concurrent medications

The outer layer of the skin, Stratum Corneum, is around 1020 m (very thin), but it is the main barrier for drug penetration

Eligible patients entered run-in phase where any OAD other than metformin were stopped and patients were prescribed glargine

This review covers recent discoveries of the GLP-1 mechanisms in the brain, including their prominent effects on obesity, and discusses discoveries that imply their potential usage in brain disorders

Effects of exenatide on measures of diabetic neuropathy in subjects with type 2 diabetes: results from an 18-month proof-of-concept open-label randomized study