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[DOI] [PMC free article] [PubMed] [Google Scholar] 117.Farokhnia M, et al

It is important not to confuse early appetite reduction with the medication failingthis is the intended first phase of action

[104] Wu CF, et al

April 1, 2026: More Lawsuits Join Vision Loss MDL for GLP-1 Drugs, Like Ozempic As of April 1, 2026, there are 73 pending lawsuits in the centralized litigation for people alleging NAION from GLP-1 drugs, including Ozempic

The most consequential pending readout is TRANSCEND-T2D-2, the head-to-head trial pitting retatrutide against semaglutide in type 2 diabetes over 80 weeks

Not mild discomfort or cramping, but sharp, severe, or worsening pain