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Additionally, tirzepatide reduces body weight and improves insulin sensitivity, both of which independently lower blood pressure over time

Begin with 10 to 15 seconds and work up to 60 continuous seconds

The abdomen (excluding a 5 cm radius around the navel), anterior and lateral thighs, and upper outer arms are all suitable sites

While it tends to be more common during the initial dose-adjustment period, it can persist for several months in some people

These may include: Upset stomach Heartburn Abdominal pain Vomiting Nausea Constipation Diarrhea Dizziness Fatigue Mild symptoms tend to resolve once the body starts to get used to the medication

None of the AEs led to premature treatment discontinuation