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Beyond the general DKD risk conferred by obesity, fat accumulation in depots anatomically close to the kidney as well as intrakidney fat accumulation has been linked to kidney disease

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Monami et al

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The inclusion of oral GLP-1s at $149/month could make these medications even more accessible for patients who prefer a pill over injections

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When it launches, it will likely be available for people with obesity or overweight plus weight-related health conditions

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While this accelerates the fat loss that drives the indirect testosterone boost, the glucagon pathway itself is not known to have a direct, independent effect on the HPTA.

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