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Over 70 percent of patients who stopped their GLP-1 medication maintained at least 5 percent body weight reduction on keto after 12 months

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This prolonged half-life permits reduced injection frequency compared to conventional GLP-1 analogs, offering improved patient adherence and sustained glycemic control [29]

This could be further confirmed by the 66.4 kDa reference polypeptide resulting in solubilities below 1 mg/mL even after prolonged incubation time (Fig