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It has therefore been considered suboptimal when evaluating treatment effects in clinical trials [71, 72]

Additionally, no association was observed between the use of GLP-1 RAs and the incidence of sunburn, herniated intervertebral discs, traffic accidents, or pneumonia

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Sugiyama C, Yamamoto M, Kotani T, et al

In clinical trials, participants lost an average of 15% of their body weight, while those on tirzepatide lost up to 24.3%