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Type 2 diabetes mellitus in adults:As monotherapy in cases of intolerance or contraindications to metformin.In combination with other hypoglycemic agents (metformin, sulfonylurea derivatives, insulin, etc.) when adequate glycemic control cannot be achieved.

A phase 2 trial finds that combining semaglutide with bimagrumab leads to greater weight loss while preserving lean mass, highlighting the importance of body composition in obesity treatment.

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