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Flint A, Raben A, Astrup A, and Holst JJ

There was also a trend towards a significant reduction in IL-6 in GE2, compared to vehicle treated, but only on the SD diet ( p = 0.054, Cohens d =0.876

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While the trials concluded at 68 weeks, we can only surmise from the data that continuing to take Semaglutide will result in continued weight loss and positive health outcomes

These findings suggest that GLP-1 medicines modulate inflammation through multiple pathways, including systemic metabolic improvements, direct actions on immune cells, and effects on non-immune cells that support interorgan communication of antiinflammatory signals (Figure 1 and Figure 2)