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People who stop using semaglutide often regain weight, with some studies reporting weight regain of up to two-thirds in the year after treatment

Cochrane Database of Systematic Reviews 2007;2:CD005613

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In addition to HbA1c measurement, SURPASS3 included a continuous glucose monitoring substudy to evaluate 24hour glucose profiles, as well as a magnetic resonance imaging (MRI) substudy to examine the effect of treatment on liver fat content and other measures, such as visceral fat