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No heterogeneity was observed among the studies ( I 2 = 0%, p = 0.84), leading to using a fixed-effect model for result reporting

What should I do if I'm experiencing severe nausea on GLP-1s

After initiation and dose increases, patients should be observed carefully for signs and symptoms of pancreatitis (including persistent severe abdominal pain, sometimes radiating to the back and which may or may not be accompanied by vomiting)

Muscle pain is another reported side effect, though less common

Allergic reactions to incretin-based therapies can range from mild local reactions to severe systemic hypersensitivity, including anaphylaxis in rare cases

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