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Description
When GLP-1 receptor agonists (GLP-1RAs) were first approved over a decade ago, their primary indication was simple: help people with Type 2 diabetes manage their blood sugar

These findings highlight the importance of targeted therapeutic strategies based on HF phenotypes
The results of the IPTW and subgroup analyses confirmed those of the main analysis

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Five clinical trials in type 2-diabetic subjects (SURPASS 15) have shown that tirzepatide at 515 mg per week reduces both HbA1c (1.24 to 2.58%) and body weight (5.411.7 kg) by amounts unprecedented for a single agent
Additionally, these are not components of FDA-approved drugs and have not been found safe and effective for any condition.At this time, these drugs are only legally accessible to clinical trial patients
