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both exenatide and metformin had similar effects on microvascular endothelial function measured by the reactive hyperemic index (RHI), as well as levels of inflammatory and oxidative stress markers including C-reactive protein (CRP), oxidized LDL (oxLDL), and vascular cell adhesion molecule-1 (VCAM-1) levels [63]
The expression of IR in the brain was analyzed semiquantitatively by western blotting
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FGF21 analogues have been observed to potently lower triglycerides in T2DM patients [948] and to promote energy expenditure in rodents
