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Whats the biggest challenge you see in applying these new guidelines in real-world clinical settings

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There have been concerns that GLP-1RAs may increase the risk of intestinal obstruction
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Major cardiovascular outcome trials and real-life observations have proven that glucagon-like peptide-1 (GLP-1) receptor agonists (GLP-1RAs), regardless of structural GLP-1 homology, exert clinically relevant cardiovascular protection
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