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If we're giving something back to someone that they already have, why does it have such a profound effect on them

Constipation tends to be more persistent than diarrhea with both medications

Sitting on the toilet for too long can stress veins in the anus

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10.1016/j.neuron.2017.10.034 156

Cryo-EM structure of the human PAC1 receptor coupled to an engineered heterotrimeric G protein
