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Although no statistically significant difference in baseline GLP-1 level was noted between responders and non-responders, it seems that the responders with more symptoms of metabolic syndrome (total fat, visceral fat and insulin resistance) react with higher insulin after GLP-1 infusion

These drugs work by mimicking the hormone glucagon-like peptide-1 (GLP-1), which regulates appetite, slows gastric emptying, and promotes insulin secretion

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Exenatide once weekly in the treatment of patients with multiple system atrophy
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Both drugs use tirzepatide a glucagon-like peptide-1, or GLP-1 as an active pharmaceutical ingredient