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Metabolic complications of psychotropic medications in psychiatric disorders: Emerging role of de novo lipogenesis and therapeutic consideration

Expression of GLP-1R V229A was again associated with significantly improved insulin secretion fold-increases to exendin-4, but in this case no changes were detected under 11 mM glucose alone conditions, with the improved fold being a consequence of enhanced insulin secretion versus WT GLP-1R during the exendin-4 stimulation period (Figure 8H, I)

The hazard ratio of the risk of pancreatitis over the study duration is shown in Table 1 and a summary of the results is highlighted in Table 2 and Figure 1

, Shaulson, E

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